I have a tizzy fit when someone gives me a "base fabric" that has a one way print on it, or worse yet, a panel. My new directive is that the hopeful person may pick one or two solid type colors, then the rest of the thing is up to me. Regarding the style, the current trend in baby quilts seems to me to be really simple, like 6" blocks, frame with 2" strips of a color, then strip again in white. You could do aqua and pink frames, or whatever suits you. You are the artist, after all.