If you are going to do hand quilting in the white part (the majority) I would hand quilt it all. When you are describing it for sale, Awesome Hand Quilted Applique Quilt sounds better than Applique quilt part hand quilted/ part machine quilted. You are more likely to get more money for a all hand quilted quilt too. However if you want it done fast, completely machine quilt it and go from there.