used wool for project that was hand quilted and loved it......have used just about all at one time or another and the only two that i do not have an allergic reaction with are warm and natural and warm and white so that is all i use now. have several friends that i do the hand sewing of the binding for and continue to have breathing problems with other battings..........my work around is to turn the entire edge and clip it with the clips that are like gymnast haircips, that limits the exposure to the allergins, FYI, if anyone else has this problem.