Misty Fuse is fusible webbing that is often preferred over Heat n Bond if you want soft appliques. The techniques to use it are a little different. If you can still see your tracing after you place the web on your fabric, just fuse to the fabric between 2 pieces of parchment paper, then cut out your tracings. Another option is to iron just the webbing between 2 pieces of parchment paper, then peel off one side. If you can see your tracing through the parchment paper, I would peel off the other side. If you can't see your tracing through the parchment paper, I would peel off the side with the tracings. You can always reinforce the tracings with a permanent Sharpie.
The biggest difference is that the appliques will be soft; Heat n Bond would make stiffer appliques.