I LOVE crazy quilting and have made many-mostly small ones though. My avatar is a 24x24 wall hanging that I made with needle turn applique in the center. You can use ALL fabrics. If it is stretchy at all (velours) it is best to back the fabric pieces before cutting them out with an iron on stabilizer (light weight). I can't think of the name of it now, but it looks like gauze fabric. I've done all hand work on my pieces.