I am right handed and I always put the end from the spool through the eye but sometimes it knots anyways. I think it's because I like loooong thread. I do love the quilter's knot though. Once your needle is threaded, you grasp the loose end and with the tail between your fingers, wrap it twice around the needle. Hold the wrap and pull it down the thread to have the knot appear at the end of your thread. I think it was Georgia Bonesteel (sp) that shared that tip?