I have done it and loved it. I moved my 'studio' back into the other bedroom when I had my LA table lengthened as that is the only room other than the garage that would actually work.
Down here the garage would be too hot in summer and dusty all year round, so that option wouldn't work for me. I prefer having my car in my garage.
Combining two room into one would also work well.
For me, I want to be able to see/listen to TV/movies when I sew. so having my sewing cabinet facing my living room is a must. Also, I don't sew well when I face a wall or window.
ali