I am in a similar situation and I have been thinking of doing the same thing! My sewing room/guest bedroom is the smallest in the house and is jam packed wall to wall to ceiling (nearly!) with quilting stuff. I even have to crawl under the cabinet to get out of the room when I use the back leaf extension! I have used graph paper and little paper cut outs to see how I could arrange everything if I used the master bedroom. So what is stopping me? I have a four poster queen size bed which I love and quilts to put on it. I would have to give these up for a twin bed in order to fit in the smaller bedroom and I cant quite bring myself to do that! But if you can manage it, DO IT!!!!!!