I've quilting a couple big quilts on my home machines. The first big quilt I did was a queen size on my itty bitty Brother. The center was a little challenging, but a few minutes and it was done and I was moving on. I don't dislike the look of SiTD, but I can't make a straight line. I find FMQ simple in comparison. Last year I bought an old singer with more room for FMQ and quilted a king size on it. My mom couldn't believe I did it myself, she though I had had a friend do it on her mid arm. It is far from perfect, but if you don't get right up and inspect each stitch the over-all look is pretty good. For me the key is to just not freak myself out. I layer, baste, and start stitching before I have a chance to get too nervous, and usually don't have more than just I rough impression of what I want to do. I just jump in and let my hands do what they would like. The last quilt I did I was going to just do a normal meander, and wound up with little swirls. I know that wouldn't work for some, but works for me
I also spray baste and not pin. I don't want to have to stop mid-stream to move pins and rearrange. I dont use clamps for the same reason. I roll and situate for where I want to start and when I have a big mess of a pile of quilt and it starts getting tough to work with I'll stop and re-roll and straighten for where I am now working. And I love Leah Days site too!