We keep our little girl on flea and tick topical (Advantix) year around or we have a scratching/biting/chewing hair off problem constantly. We had her on Frontline Plus until this year and it seemed not to be doing the job of keeping ticks off her. DH found 2 ticks buried in her skin the first of March and decided to change to Advantix.
So far, it seems to be doing the job.