Here's a sample of a beautiful one I came across the other day:
http://sampaguitaquilts.blogspot.com...fly-quilt.html
Here's another one from this board - she pieced her back but not into blocks.
Mixed opinions on whether or not she should cut it up into squares/blocks, but I think it looks sensational like it is:
http://www.quiltingboard.com/picture...p-t203629.html
It should pose NO problem for your LA-er, and actually might free her up artistically as there are no "confined" spaces to quilt.
I think it's a great idea.
What kind of motifs are you considering?