I'm fairly new to quilting, but I've done a few applique projects. Here are some of my thoughts as I've learned so far:
My machine has a blanket stitch and an applique stitch. The applique stitch looks similar to blanket, but the result is a little better looking. The downside is that it's more limited on stitch width and length compared to the blanket stitch.
I do vary my width & length based on the size of the applique piece.
Also, I change my thread color to match or coordinate with the applique piece. I've also used varigated thread on applique with good results. Depending on the piece I like using a shiny rayon, or else I use a standard poly.
Someday I'd like to learn needle turn, but for now I'm enjoying the heck out of machine applique...