Glad that you and your DH have now got it re-marked and are ready to go!!
Maybe he'd help with the stitching?
I'm totally in awe of your making 7,000 yo-yo's!
Is there a colour/fabric placement plan?
... or is it if totally a scrappy look, wherever they land on the quilt?
One big marathon ahead ... then again, maybe it's seems easy now that you're on the home stretch of having made all of them?
As to the how to? ... for me ... I'd just sit down on my couch, feet up and let the quilt puddle around me ......... and not plan on any quick get-aways, once nestled in.
And oh yes ... I'd have all my stitching supplies at hand, including the TV flipper for a good movie or music!
I'll sure be looking forward to seeing any progress pics, as you go!