Here is one I did for my hubby's 60th BD. starting with his early pics , university, meeting me, our kids, daughter's wedding, and a few professional shots (he is a musical conductor/composer). Sorry I cut off the bottom of the photo-it is balanced with a full photo and a bit of red and black border so it is finished.
Because this was going on the wall I wanted the photos on point like a scattering of photos for visual interest. (This is sooo easy to do--just make a huge border around the block then slap your square up ruler on it and twist it a bit.) I also took some creme fabric and printed out favorite sayings from his life and appliqued them on. And a little red for interest. Had all the guests to his party sign the back.