I have quilted a few quilts on my Janome 6600 cot, single and what I think is called a twin in the USA, in the UK we call it a double. Again just meandering FmQ on the larger sizes but on the cot size I have started to be more adventurous. I think the most important part of quilting on a domestic sewing machine is making sure you have really sandwiched the quilt well and that there are no creases in that bottom layer......for me sewing the quilt altogether is the very best part....suddenly the quilt gest life and it changes from a caterpillar into a butterfly. I dream of a mid arm or a long arm but don't think I'll ever save enough to get one, but I also don't like the thought of someone else finishing what I have started so wouldn't ever send a quilt off to be done......but that is just a personal view as I know a lot of people do and they look amazing.