I made and quilted about 100 large quilts (king/queen) on my regular home machine before my arthritis got too bad for this. A large percentage of those won blue ribbons. Almost all of the work was FMQ. It is certainly possible, but time consuming. When I switched to a Janome with a slightly longer arm, it became easier. My guild owns a lovely LA, but I am not physically able to use it. One does what one can.