Becareful with any cortisone ointment and the strength for infants, children, etc is different from that of adults. Ensuring that the area is dried well, helps (if you can leave the diaper off, it's great, even for a short time). Any ointment (Desitin, A & D) that provides a moisture barrier will work, some rashes are yeast/fungal based so an over-the-counter treatment (recommended by pharamacist) is helpful. Mary Kay's extra emoillent night cream is a great product to try...amazing how it works. When in doubt or no improvement get to MD....dietary allergies become a big cause as well as detergent on clothe diapers, and brand of disposable diapers can make a difference. Best of luck.