First, a couple questions. Is this quilt going to be used on a bed or as a throw and eventually laundered? If it is, I'd say to eliminate the last pattern with the raw edges. I'd be afraid of raveling in the future. The first one with the stripes going across, will be very easy and fast to put together. The second one is still made from strips but more time needed because of how the blocks are sewn together. The second one will also give more of a checkerboard appearance, I think. It's up to you. You are quite ambitious to tackle a queen size quilt for your first quilt to make! :wink: Good Luck!