I am working on one right now that has both regular cotton and batiks just to get the coloration that I want. I have read several posts on here indicating that it works, so I am giving it a try. It does handle differently as in a bit firmer weave. I have heard hand quilters say that it is also harder to quilt. Don't know if that helps you or not, but I wanted these colors and that's the only way I could achieve them.