I do have my sewing/quilting in 2 different rooms and on 2 different floors. At one time, I had a 12' quilt frame (& sewing machine) in an entirely different basement room, but had to give that up for a son returning home to live. Upstairs is machine sewing/machine embroidery and pressing/ironing. Downstairs is everything else ... cutting, storage, serging, quilting ... by machine and by hand. The setup works well for me and I need the exercise going up and down the stairs (because, unfortunately, our exercise equipment rarely gets used).