I use 2 rooms & this is what I have: B'room #1 - My 3 sewing machines are in there + my serger & 2 cabinets for various sewing things (lots of sewing things !!) + I use the double closet for storage for books etc.
B'room #2 is my cutting & pressing room. I find that makes me get up often & that's good for my ailing back. Sitting for too long is not good for it. I have a sofa bed in there too so space is at a premium. It also holds a cabinet for sewing fabric (not quilting fabric) & the double closet is for extra clothes + all my quilting fabric.