Any medallion quilt would look great. A paper pieced Mariner's compass, Lone Star, carpenter's wheel, ...
Any big block would make a nice medallion. Then you could do borders of different colors and widths.
I would make the center no larger than about 45 - 50" so that the quilt could be used on a smaller bed.
Easy would be Amish (large square with different colored borders, and setting triangles - can be set on point).