generally my quilts get a rinse after the quilting, as I usually use some kind of marking technique that needs a rinse out. any spray starch or sizing that i use in the process of piecing gets rinsed out at that time as well. So far, so good. No problems. I've been using the 505 spray since it came to spring quilt market in Providence RI, which i think was about 7 or 8 years ago now.
If I have fabric that should not be rinsed for some odd reason, then I probably would not use the spray or the marking tools, but that is not usually the case.
Lisa