My sewing room keeps getting moved around and I have had it for 7 years years. At first I wanted to have my sewing machine so I could look out the window, but then it was too bright, so I moved my sewing machine so that it is perpendicular to the window and my embroidery machine next to the window. Even though I keep the shades drawn unless I am in the room. The majority of my fabric is wrapped on comic book boards, in bins and stored in the closet. My cutting table is also a full length mirror that folds up and out of the way, so if you can keep your cutting table out of the way except when you need it may be help you feel more open. I like to have my ironing board set up and I have the large board ironing board to put on top when I want to iron yards of fabric - also, some times I put my cutting mat on it when I am just cutting small pieces and don't need a lot of room.
You really need to see what you have and what fits your movements. Even though I am right handed for most of my working years I had a left handed desk and so most of my sewing area is set up is like my work was - it's what is comfortable to me. But as time goes by I move things around.