My only experience with a prayer quilt was for one of my friends, a fellow quilter, who was fighting breast cancer. I made a quilt with HSTs - one side with pastels (light) and the other side navy blue (dark). I sewed it together with all the lights pointing up, then pillowcased it with Minkee and sewed in the ties. Then I presented it to the church, asked members to sign a light triangle with a prayer or verse and to tie one of the knots, praying as they tied it for her health. Since she had for many years been a Sunday School teacher, I took it into her class rooms during class and got her past students to sign it and tie a knot, too. She took that quilt to the hospital with her and to everyone of her chemo treatments.