I chain piece, but usually make blocks in batches - depending on the intricacy of the block, usually 5 to 10 at a time. I like breaking up the tasks a bit. Sew some, press some, square up some, then start over. I'm working on a 100 block project now where each one is different, so I choose individual fabrics and cut each one. I tend to have the same approach with that. I'll stack up 10 - finish them, then start again.