I always wash my quilts first, for all the same reasons as everyone else. I do let the recipients know that it has been washed and dried and if it bled or not. If it does, even just a little, they get a couple of color catchers with it. I do pre- wash my fabric with color catchers.
I just gave a trainer from my gym a quilt for his 5 month old son. He said his wife really loved it and said it looks to nice to use. I told him that I make quilts to be used, so use it. If it does need any minor repairs in the future, let me know so I can fix it to be used more.