I made some quilts that were cotton tops and fleece as backing. I didn't use batting. I was MQing using a free motion foot. I pin basted as I usually do, putting the pins a little closer together because of the stretch in the fleece. I really didn't have any problems machine quilting except my bobbin case was stuffed with fibers so I had to remember to keep dusting it out. When I finished....yes the cotton was a bit puckered but that's the way I like my quilts. I did have a problem with the feel of the quilts.....they were a bit floppy but my daughter reminded me that some people like their quilts floppy....I like the feel of the cotton on cotton.