I am a huge fan of Invisifil for quilting. I run it through my longarm no problems and they operate much faster and put much more strain on thread than a domestic. I'm not sure I would use it for piecing. It is much better suited to applique work and quilting where you only want texture to show and not the thread. When I use invisifil I usually am running a prewound magnaglide in the bobbin but my friend has used it in both with no issues.