Okay here is another factor to consider--your batting. Warm and Natural will shrink about 4%. Poly batting will not shrink. Hobbs 80/20 will also shrink about 4%.
I always wet my fabrics with as hot a water as my hands can stand and dry in a hot dryer--to check for excessive colour bleeding and minimize shrinkage. But also because I do not care for the sizing that is in the fabric. It tends to inhibit my ability to breathe--which I think is sort of necessary for the whole continuance of life thing.
It depends on the look that you want your final laundered product to have--totally flat with no 'crinkling' or some to moderate 'crinkling'. The amount can be controlled by the denseness of the quilting and/or the choice of batting.