Two guilds I belong to - Palmetto Quilters meet at the Grand Strand Senior Center in Myrtle Beach, meets on Wednesdays 9 - 12, and Grand Strand Quilters meets on Thursdays from 10 - 12 at the base recreation center on Gabreski Road in MB. Obviously, I live in MB area, too!
In addition to the shops mentioned by others, there is a Hobby Lobby in North MB and, of course, Walmart, for fabric.
Hope to meet you soon after you move here!