You will definitely be able to do the jersey quilt as a beginner, but maybe not as your first quilt. You will be dealing with stretch and stabilizers which are not hard to work with after you know a thing or two about quilting, but you may wish to do a basic quilt in a small size (I saw the word "huge" in your message) with regular cotton fabrics to begin with. This will teach you some basics. "Huge" and "stretch" is only one quilt away