I have used this many times with Frixion or Crayola Ultra-Clean markers to transfer my designs. Shorten your stitch length a bit to facilitate removal, but if the quilting is dense it can be difficult to remove. I found THE BEST way to remove the Press and Seal from tight areas is to use the eraser end of the Frixion pen or a clean white artist's eraser. It grabs the plastic wrap and makes removal a breeze.