I watched a youtube video of Elenor Burns using a serger for a Log Cabin quilt. I remembered thinking that if she does it, it must be okay. I just got a serger for Christmas, so I've never used it for quilting, just for garments. If you are comfortable with one, it should be fine.
I'm totally going to serger the edges of my next quilt before sending it to the long armer! Love that idea!