Do you want to do a sampler, which is usually all different blocks or do you want to do what Noriko did and do the same block but make them appear drastically different by color and value placement? Two entirely different animals IMHO. Norikos quilt consist of Lucy Boston blocks, An EPP method made with elongated hexis, at least as best I can make out from the picture. The hexis are fussy cut for the same repeat of fabric in the different areas so she can get those drastically different looks from the same block.
Have you viewed any of the pictures of the 365 day challenge quilt? That is fabulous sampler done scrappy but it is given continuity by value placement.