Your question prompted a few thoughts I had not had before. A serger goes really fast, does not have a bobbin thread to worry about, and most can be adjusted to make a quarter inch seam. right off the top of my head, I wonder if those Jelly Roll quilts could not be done with a serger? Gonna pay attention to answers to this and see what others have to say. Love my serger and really don't use it enough.
What a great question....