Make sure your needle is the correct size for the thread. I always start from the middle and work my way to the edges. Use a walking foot. Do not sew around the edges until you are done, the quilt stretches a bit, even when pinned. I sew a big + through the quilt, that way the quilt is divided into 4 parts. Sew up one side and then go the opposite way. You can do a continuous stitch , up and down and back and forth, then cross way.