The only piece so far where I've used wool batting was an art quilt that I did a layer of wool batting over a layer of bamboo. I wanted the wool for it's loft as there were some areas in the quilt that I wanted to do some faux trapunto. It worked beautifully for that. I did find that it was a little more slidey (if that's a word) while quilting when used as a layer over the bamboo--I'm not sure if that would be a problem with it if used on its own.
Rob