Yes...absolutely go on this cruise. I've cruised to Alaska and the quilt shops are wonderful. Unique fabrics to the region and culture. There are many off-ship excursions you could do despite physical limitations. I imagine the "quilt" cruise will be designed to cater to the quilter's aboard but, no doubt, they expect hubbies to go and will have activities for them, as well. I think this is a wonderful gift from your husband. Amd the climate the time of year for cruises is mild, light weight clothing, but still, on occasion, long sleeve or rain gear. With MS, you should not have any negative effects (my sister has MS), but check with your doctor before you go and meet the physician on board shortly after sailing. Don't miss this opportunity!!!