The throat size on a 201 is about 7 1/2 or 8 inches, so a little smaller than your other Singer. Yes it can be done, there are lots of quilters who quilt their own quilts on a domestic machine. For me, the issue wasn't so much maneuvering the bulk of the quilt around, it was how hard on my hands pushing the quilt around is.(I have arthritis in my hands). I could only do small quilts on my domestic machines because of my hands so when the opportunity arose I bought a long arm.
Cari