I love to hand quilt and have found the 14 inch plastic square works for me because I like to do 12" blocks. I do not have to move the fabric so often. Also, my favorite thread is YLI. It is strong and I find it does not knot as badly.
What ever works for you it what you need to use. It may take awhile to be comfortable with anything. Hand quilting is so relaxing for me, while some of my quilting buddies hate it.
Just enjoy!