Another way to break up the ( busyness) is to frame the blocks with sashing strips in solid colors. I like the diagonal settings in quilts, on point would also be fun. Alternating with solid blocks certainly adds interesting elements too. I would lay out blocks and ( play) with options for a little while to determine what is most appealing. For simple options I would probably use black sashing strips - depending on what the busy fabric looks like maybe white corner stones too.