my animals are not allowed in the room I quilt in--but I have taken a quilt off the frame to turn for borders, or because I needed to put another one on for a rush job, etc. I'd suggest if you are planning to take one end off every time you finish quilting that you start using zippers instead of pins to put the quilt on--would say a lot of time.
Barb--have you ever seen the YouTube video on how to add to the backing without taking it off the frame? I just had to use that and it works--although her demo is with a small wallhanging and I had a 100"quilt on, so was a little more time consuming! Next time I definitely will measure more carefully!