I leave the pre-cuts whole. On a very rare occasion I will break up a jelly roll. Part of the joy, for me any way, is that the fabrics in the pre-cut are from the same line and I do not have to worry about colors going together. That said, also on occasion, I will add to a layer cake or jelly roll to make a bigger quilt or two baby sized quilts from one pre-cut. In the end, it all depends on the quilt I am making. For me the worst is open up a pre-cut using part of it and then adding to my pile of scraps! Yuck! I have all I need now.