I've considered moving all my sewing out to the Machine Shed - but it does not have a bathroom. DH and I were just talking about downsizing when we retire, and I told him that a sewing studio that I can fit the LA and my working machines in is a must. I'll probably have to rehome most of my machine collection, but I've got several years before that is an issue.
At one point I had my LA set up in what was the dining room. The biggest problem was that it's open to the kitchen and no way to close that off, so I could not keep the cats out. And they thought it made a really good hammock! I'm OK with having to share my sewing room with the cats, but did not like that. I love knowing that if I have a quilt on the LA - it's not going to get messed with by anyone but me.