I often use cuddle fabric for backing and have not had any problems quilting it on my DSM. I don't do anything different with it than I do with cotton. I only do pin basting pinning liberally. When I first started using it, I hadn't heard anything scary about it so I just proceeded to quilt it. It does leave droppings when you cut it. You might take it outside and give it a shake after cutting, but after that it is fine. I like the way the quilting sinks into the back. Although, some types show more than others. I love it and so do my recipients. Other than cuddle, I use flannel. I like to have a cozy backing.