I haven't tried Nespresso, but I have a Hamilton Beach K-cup maker. After trying the Keurigs, I think the Hamilton Beach makes a richer cup of coffee. I even got to do a pre-market home test of one of the newest Keurigs (the one with the milk frother) and was happy to return to my Hamilton Beach.
We typically brew regular coffee because we like that better than anything. However, if we want a decaf cup or we just didn't get enough with the regular pot, we make an extra cup in the K-cup maker. We also like to travel with it, because it makes a better cup than the best hotel coffee.
We buy our pods at Costco or at the grocery store when they have their typical end of year sales. It's definitely more expensive to use pods of any kind, but oh so very convenient.