I use silk thread for hand applique all the time - Gutermans is what is available here at Joann's so that's what I use. I try to match the piece I'm appliqueing to the thread, but sometimes I use gray if I can't match it well. I also have a strange greenish beige that works well. I don't use long pieces of thread when I applique so find I don't get many tangles. Give it a try!