It would be on a fabric by fabric basis. Part of what makes quilting fabric what it is, is an even weave so we should be able to turn it one way or the other. But if there is any sort of treatment or coating, (including on the threads that are woven) it can reflect differently. Sort of like corduroy up one side and down the other. If you can see it on the bolt, simply turn back a corner and get back about 6 feet and look at the turned up corner compared to the fabric still wrapped around the bolt.
But any difference (if any at all) is likely to be very subtle and this is the back we are talking about. I think you will be ok. To help hide seams, if you can, choose a print.