I'm so sorry about your health problems, I have MS too. I think it depends so much on whether you plan to do the quilting by hand, on your machine. if you work, or howe much time you can spend on it, and the intricacy of your design. Simple block design could just take like a week to piece the top, while an intricate design could take much longer. I believe there is no right answer on time - just enjoy doing it and take it at your own speed. Good luck with everything! :thumbup: